Few studies have directly compared the renoprotective effects of angiotensin II–receptor blockers and angiotensin-converting–enzyme (ACE) inhibitors in persons with type 2 diabetes. In this ...

Glycogen phosphorylase (GP) is a pivotal enzyme responsible for the catabolism of glycogen into glucose, a process intricately linked to blood glucose regulation. In the context of type 2 diabetes, ...

In a new study published in Science Signaling titled, “Restoration of striatal neuroprotective pathways by kinase inhibitor treatment of Parkinson’s linked-LRRK2 mutant mice,” researchers from ...

A protein kinase inhibitor is a type of enzyme inhibitor that can block the action of protein kinases. Protein kinases add a phosphate group to a protein in a process called phosphorylation, which can ...

Bethesda, MD – A report in the Journal of Biological Chemistry shows that inhibition of heme oxygenase-1, an enzyme involved in iron metabolism, reduces Kaposi sarcoma tumor growth. This discovery ...

Putting the brakes on an enzyme might rescue neurons that are dying due to a type of Parkinson’s disease that’s caused by a single genetic mutation, according to a new Stanford Medicine-led study ...

Scientists have deciphered the structure and functional mechanism of the glucansucrase enzyme that is responsible for dental plaque sticking to teeth. This knowledge will stimulate the identification ...

Grapefruit juice is more than a breakfast staple — it’s a potent enzyme inhibitor that can dramatically alter how certain drugs are metabolized. This article explores how a tiny structural difference ...