Seattle researchers have developed a technique to quantify the changes in gene activity that occur throughout zebrafish embryos in response to specific edits to key genes. The approach makes it ...

The heartbeat is synonymous with life. It's one of the first essential functions to begin during development and to end at death. "The heart is one of the first organs to form and function during ...

To arrest heartbeat pharmacologically, embryos were treated with 0.65 mg/ml tricaine (Sigma-Aldrich) in E3 embryo medium for 30 min. They were maintained in E3 with tricaine (0.1 mg/ml) during imaging ...

Metformin is an antidiabetic drug used in type 2 diabetes as well as indicators in polycystic ovary syndrome (PCOS) and cancer. Due to their increase in popularity, high amounts of metformin are being ...

Researchers confirm using zebrafish that if a certain gene is not excluded when vertebrate embryos are developing, the notochord will not elongate properly, resulting in a shortened form. Can a single ...

Scientists headed by a team at the Chan Zuckerberg Biohub San Francisco (CZ Biohub SF) reported on the development of Zebrahub, a dynamic, state-of-the-art atlas of zebrafish embryonic development.

When early cartographers undertook perilous expeditions to map unknown corners of the world with sextants, compasses, and hand-drawn diagrams, it’s unlikely they imagined that someday anyone with an ...

How does a tiny cluster of cells become an embryo with a head, trunk, and tail? And how do thousands of genes coordinate this development? A new imaging method makes it possible to visualize the ...

Five zebrafish embryos in a tiny drop of water. The yolk sac is clearly visible, with the first two cells located at its tip. Hair, nails, and horns, all made up of keratin, are some of the hardest ...

Congenital heart defects (CHD) occur in 1 in every 100 babies born daily in the United States of America. Although CHD can be surgically repaired, it has been shown to complicate heart health with ...

In recent decades, the zebrafish has become one of the most valuable model organisms in scientific research. For a variety of reasons, including their genetic similarities to humans, these tiny ...