Antigen discovery technologies have largely focused on major histocompatibility complex (MHC) class I-restricted human T cell receptors (TCRs), leaving methods for MHC class II-restricted and mouse ...

According to a new study published in Nature Communications, researchers at the Department of Laboratory Medicine, Karolinska Institutet, have made a significant leap in drug discovery and development ...

A research team led by Dr. Xiaoyu Li from the Research Division for Chemistry, Faculty of Science, in collaboration with Professor Yizhou Li from School of Pharmaceutical Sciences, Chongqing ...

Biomarker research has made substantial progress recently beyond the proverbial low-hanging fruit. Emerging technologies and techniques are helping make biomarker detection and application faster, ...

Scientists have uncovered potential therapeutic avenues for metabolic diseases. "Metabolism" describes the body's chemical changes that create the necessary materials for growth and overall health.

Copy number variants (CNVs) are major contributors to genetic diversity and disease. While standardized methods, such as the genome analysis toolkit (GATK), exist for detecting short variants, ...

STARKVILLE, Miss.—New mathematical tools revealing how quickly cell proteins break down are poised to uncover deeper insights into how we age, according to a recently published paper co-authored by a ...

Until now, scientists typically studied the changes of proteins and their roles in the cell by using a fluorescent tag to label and follow one protein at a time. This approach limited the number of ...

Every graduate student, creative person and inventor of any stripe has experienced periods when nothing seems to come together, some of us many times. I was waist-deep in such pit after a year-long ...

The two main approaches for discovering disease genes reveal distinct aspects of biology, a new study shows. While both methods are widely used, the research found that they identify different genes ...

A research team has developed a new drug discovery method targeting membrane proteins on live cells. A research team led by Dr Xiaoyu LI from the Research Division for Chemistry, Faculty of Science, ...